The educational program has already reached 1,000 women, but researchers want to grow the program and make it easier to get counseling and testing.
Researchers urged other oncologists to look for ALK rearrangements in GI patients and try to get them on ALK inhibitors through trials or compassionate use programs.
The company is conducting a clinical trial of a pan-variant inhibitor for KIT-mutant GIST and hopes to advance an EGFR pan-variant inhibitor to the clinic soon.
Experts are working through challenges to make low-cost sequencing available at resource-limited hospitals around the world, starting with an institution in Pakistan.
Novartis' JDQ443 showed a 45 percent response rate in advanced KRAS G12C-mutant non-small cell lung cancer patients.
Because of the success of this legislation in encouraging drugmakers to study single agents in pediatric indications, advocates want to now urge research into combination therapies.
Early data on AZD5305 showed it is highly tolerable and suggested it may be amenable to combination and prevention strategies.
In a biomarker analysis, the researchers found KEAP1 co-mutations and low tumor mutation burden may be predictive of outcomes on Lumakras.
Based on the results, the researchers hope to standardize a process at Penn Medicine for ordering plasma NGS at the time of NSCLC patients' diagnostic biopsy.
Pfizer, a major player in the space, is exploring two drugs targeting CDK2 to circumvent resistance to CDK4/6 inhibition in HR-positive, HER2-negative breast cancer.