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Ciara Curtin

Editor, Daily Scan
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+1-212-651-5627
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[email protected]

Ciara Curtin writes science features for GenomeWeb and is the editor of the Daily Scan and Careers blogs.

Articles Authored by Ciara Curtin

Nov 23, 2020

Tumor, Germline Testing of Cancer Patients Can Give Discordant Results

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A study presented at the NSGC annual meeting found that tumor analysis and germline testing yielded discordant results in almost a quarter of cases.

Nov 23, 2020

Multigene Panel Germline Testing of Cancer Patients Detects Unexpected Pathogenic Variants

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The study, presented at the NSGC annual conference last week, supports the broader use of panel testing for cancer patients suspected of hereditary disease. 

Sep 09, 2020

T-Cell Immunotherapy Targeting AML With CBFB-MYH11 Fusions Headed for Human Studies

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Fred Hutchinson Cancer Research Center investigators engineered T cells to recognize a protein expressed by acute myeloid leukemia cells with a CBFB-MYH11 gene fusion.

Jun 25, 2020

SEngine's Organoid Testing May Reveal Patient Sensitivity, Resistance to Cancer Drugs

Initial data on the PARIS test, combining functional drug testing and DNA sequencing, showed concordance between its predictions and patients' treatment responses.

Apr 30, 2020

Vitrakvi Effectiveness Does Not Extend to NTRK Alterations Beyond Gene Fusions, Study Finds

The analysis presented at the AACR Virtual Annual Meeting confirmed the effectiveness of the TRK inhibitor to treat cancer patients with NTRK gene fusions.

Apr 29, 2020

EMBRACA Trial Shows No Overall Survival Difference Between Talzenna, Chemotherapy Arms

Additional analyses found the talazoparib arm reported a better quality of life and a limited effect of broader tumor genomic markers on clinical benefit or progression-free survival.

Apr 02, 2020

Full BRCA1 Gene Deletion Suspected to Contribute to Patient's Long PARP Inhibitor Response

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The large BRCA1 deletion, which was not captured by initial genetic testing, might be the reason for the patient's exceptional response to a PARP inhibitor. 

Jan 28, 2020

Study IDs Biomarker of Treatment Efficacy for CDK 4/6 Inhibitors in Breast Cancer; FDA Filing Planned

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The Swedish firm Biovica said this and additional studies will form the basis of a US Food and Drug Administration submission for its test measuring thymidine kinase-1.

Jan 06, 2020

Organoids Fuel Development of Gene Expression Approach for Tailoring Pancreatic Cancer Treatment

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The organoids could be grown to contain cellular features of the original tissue samples, enabling them to better mimic what occurs in the body than two-dimensional cultures.

Dec 03, 2019

Classification Algorithm Divides Pancreatic Cancer Patients by Likely Treatment Response, Outcome

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The classifier, called PurIST, can be applied to various pancreatic cancer sample types and different gene expression platforms, which may improve its clinical applicability.

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