Advances in Clinical Genomics Profiling
Immunotherapy Response Data Spurs International Effort to Uncover Germline Polygenic Predictors
Premium
More than 45 centers are collaborating to uncover germline contributions to immunotherapy response and resistance and bring polygenic predictors to the clinic.
Gene Expression Score IDs PD-1/PD-L1 Immune Checkpoint Inhibitor Resistance in Bladder Cancers
Researchers said that the score further may identify patients whose treatment resistance may be overcome with combination strategies targeting certain cells.
Liquid Biopsy MRD Detection Eyed as Decision Tool for Oligometastatic Colorectal Cancer Patients
Premium
If the team is successful in expanding on the results that they reported last month, it could open a new application for the still nascent circulating tumor DNA technology.
Broad Team to Improve Minimal Residual Disease Detection With Mutation Enrichment Sequencing Method
Premium
The team plans to integrate the method, which combines mutation enrichment with duplex sequencing, into its platform to detect minimal residual disease in blood.
MSK Team Explores Clinical Utility of Germline Testing for Pediatric Cancer Patients
The researchers found that 18 percent of pediatric cancer patients tested with MSK-IMPACT harbored one or more inherited risk mutation.