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News on biomarker discovery and validation for research and diagnostic use in genetics, genomics, and molecular diagnostics.
Overexpression of immunoproteasome components PSMB8 and PSMB9 were found to be predictive of improved survival and response to immunotherapy.
The trial will assess vopratelimab and Jounce's PD-1 inhibitor in NSCLC patients, and evaluate the ability of an RNA signature to predict response.
Extending a prior agreement with the drugmaker, Personalis will use its DNA/RNA platform to identify both predictive biomarkers and resistance mechanisms.
The Swedish firm Biovica said this and additional studies will form the basis of a US Food and Drug Administration submission for its test measuring thymidine kinase-1.
Researchers have identified immune cell gene expression signatures that could one day be developed into tests to predict response to treatment.