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NEW YORK — Grail said today that it will collaborate with three global pharmaceutical firms — Amgen, AstraZeneca, and Bristol Myers Squibb — to evaluate its methylation-based technology for the detection of minimal residual disease in early-stage cancer patients.

Blood-based genomic tests to detect MRD have emerged rapidly in recent years, with multiple companies exploring a variety of platforms. The most prominent so far have been assays like Natera's Signatera, which use sequencing data from tumor tissue samples to develop patient-specific liquid biopsy assays.

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