clinical trial
I-Mab Begins Study of Uliledlimab Plus Tecentriq in Advanced Solid Tumors
The firm will evaluate the combination's efficacy and potential biomarkers of response in patients with ovarian cancer, head and neck cancer, NSCLC, TNBC, and other cancers.
Rain Therapeutics Begins Basket Trial Evaluating Milademetan for MDM2-Amplified Solid Tumors
The Phase II MANTRA-2 trial will enroll roughly 65 patients with tumors harboring wild-type p53 and a prespecified minimum MDM2 gene copy number.
OSE Immunotherapeutics Randomizes First Patient to Phase II Trial of Vaccine in Metastatic NSCLC
The trial is evaluating its neo-epitope-based vaccine Tedopi in combination with nivolumab or chemotherapy, as compared to chemotherapy alone.
Sermonix Pharmaceuticals Raises $40M to Further Develop Lasofoxifene for ESR1-Mutated Breast Cancer
The firm plans to use the funds from the series A3 financing round to bring its selective estrogen receptor modulator through late-stage clinical trials.
Drugmakers Trying Out Decentralized Clinical Trials in Precision Oncology Though Risks Remain
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The pandemic increased interest in virtual, tech-enabled enrollment strategies, but pharma wants to see if early studies succeed before jumping in.