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NEW YORK – Results from the Phase II monarcHER study published last week in Lancet Oncology demonstrated that women with advanced HER2-positive breast cancer may benefit from a combination of three non-chemotherapy agents: the CDK4/CDK6 inhibitor abemaciclib (Lilly's Verzenio), the HER2-targeted therapy trastuzumab (Genentech's Herceptin), and the anti-estrogen therapy fulvestrant (AstraZeneca's Faslodex).

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Dec
02
Sponsored by
Qiagen

The Phosphoinositide 3-Kinase (PI3K) pathway is one of the most frequently altered pathways in human cancer and plays a significant role in disease progression and resistance to endocrine therapy.