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CRISPR Framework Helps Identify Combination Therapies for Optimal Targeting of KRAS Mutant

May 29, 2019
|
staff reporter

NEW YORK (GenomeWeb) – Researchers from the University of California, San Francisco used a genome-scale CRISPR interference (CRISPRi) functional genomics platform to systematically identify genetic interactions with a mutant form of KRAS called KRASG12C, and found combination therapies that target genes involved in its activity.

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