NEW YORK – Columbus, Ohio-based Sermonix Pharmaceuticals said on Wednesday that it is collaborating with Eli Lilly in an upcoming Phase II trial studying Sermonix's lasofoxifene in combination with Lilly's CDK 4 and 6 inhibitor abemaciclib (Verzenio) in estrogen receptor-positive, HER2-negative metastatic breast cancer patients who also harbor an ESR1 mutation.
The trial, which is expected to start enrolling patients in the third quarter of 2020, will evaluate the safety of the combination treatment.