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NEW YORK – A team led by researchers at the National Cancer Institute has analyzed advanced cancer patients known as exceptional responders to therapy — those who survive significantly longer than individuals with clinically comparable tumors — and found plausible mechanisms for some related to DNA damage response, intracellular signaling, immune engagement, and genetic mutations.

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Dec
02
Sponsored by
Qiagen

The Phosphoinositide 3-Kinase (PI3K) pathway is one of the most frequently altered pathways in human cancer and plays a significant role in disease progression and resistance to endocrine therapy.