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Home › Disease Areas › Cancer › MacroGenics' Margenza Improves PFS Over Herceptin in Phase III Breast Cancer Trial

MacroGenics' Margenza Improves PFS Over Herceptin in Phase III Breast Cancer Trial

Jan 25, 2021
|
staff reporter

This story has been updated with details about an additional trial in the neoadjuvant setting.

NEW YORK – MacroGenics published results in JAMA Oncology on Friday from the Phase III SOPHIA trial demonstrating the ability of its monoclonal antibody margetuximab (Margenza) plus chemotherapy to extend progression-free survival in metastatic, HER2-positive breast cancer patients compared to trastuzumab (Genentech's Herceptin) plus chemo.

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