Novartis Seeks FDA OK for Drug With Favorable Phase III Results in PIK3CA-Mutated Breast Cancer

NEW YORK (GenomeWeb) – Novartis has filed a new drug application with the US Food and Drug Administration for its investigational drug alpelisib — an alpha-specific PI3 kinase inhibitor that shows promise for treating hormone receptor-positive, HER2-negative advanced breast cancers with PIK3CA mutations.