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CHICAGO (GenomeWeb) – Researchers are on the hunt for germline or somatic risk variants that might serve as markers for predicting immune-related adverse events (irAEs) in individuals treated with immune checkpoint blockade-based immunotherapy.

At the American Society of Clinical Oncology annual meeting here on Friday, Cleveland Clinic medical oncologist Vamsidhar Velcheti touched on the spectrum of toxicity events that are being reported as individuals with cancer are treated with drugs designed to tinker with the immune system.

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NTRK fusions are oncogenic drivers in a variety of tumors.

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This webinar, Part 3 of the “Advances in RNA-based Biomarker Development for Precision Oncology” webinar series sponsored by GeneCentric Therapeutics, will discuss novel and emerging applications of RNA-based genomic analysis in precision oncology, form characterizing the tumor microenvironment to informing the development of immuno-oncology treatments.

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Circulating tumor DNA (ctDNA) can allow clinicians and researchers to better understand which patients are at high risk of recurrence and should be offered intensified chemotherapy or selected for clinical trials.


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