NEW YORK — Genetic testing of tumor and germline samples of cancer patients can give discordant results, according to a new analysis presented at this year's virtual annual meeting of the National Society of Genetic Counselors.
Genetic testing of tumor tissue is increasingly performed as part of personalized cancer care to search for alterations that indicate a tumor may be susceptible to targeted therapy. But while tumor testing can also reveal germline alterations that may inform therapy choices, results from tumor and germline testing are not always the same.