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NEW YORK – The UK's National Institute for Health and Care Excellence published a final draft guidance on Thursday recommending pembrolizumab (Merck's Keytruda) as a treatment for certain advanced head and neck cancer patients.
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The Phosphoinositide 3-Kinase (PI3K) pathway is one of the most frequently altered pathways in human cancer and plays a significant role in disease progression and resistance to endocrine therapy.