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The FDA granted priority review status to rucaparib for prostate cancer patients with BRCA1/2 mutations.

Among the firms presenting, drugmakers, speciality biotechs, and genetic testing firms provided an update on their precision oncology development programs.

Using corrected TMB and other variables allowed Johns Hopkins researchers to more accurately predict response to immune checkpoint blockade in lung cancer.

The companies will develop tissue-based companion diagnostics for Amgen's investigational treatment AMG 510 for non-small cell lung cancer.

The finding suggests that African-American patients may be more likely to respond to treatment with poly ADP ribose polymerase (PARP) inhibitors.

With the participation of five cancer centers and clinics, Taproot is hoping to build a national, prospective data registry that is much needed but has been difficult to advance to date.

In NSCLC driven by MET exon 14 alterations, research indicates Xalkori had some activity.

The worldwide license provides Iovance Biotherapeutics exclusive rights to Cellectis' TALEN gene editing technology for multiple gene targets to modify TILs for treating various cancers.

Genentech will use Adaptive's ClonoSeq assay for MRD testing in a CLL study. Adaptive will receive upfront and sample testing payments of undisclosed amounts.

Insight's portfolio includes a gene expression-based immuno-oncology assay for therapy response prediction.

Such prognostic information could aid clinicians in making decisions about radiotherapy for postmenopausal women with breast cancer.

The company is beginning a multi-site Phase II trial designed to establish that its approach can identify patients who will respond to immuno-oncology drugs.

In the trial that led to Ayvakit's approval, 84 percent of patients with PDGFRA exon 18 mutations saw their tumors shrink.

Acepodia's off-the-shelf cell therapy uses an antibody-cell conjugate to target human HER2-expressing solid tumors.

The multi-center registry study aims to measure the clinical impact of serial testing with Signatera in patients with stage II or stage III colorectal cancer.

The company will submit the data as part of a new drug application for pralsetinib for RET fusion-positive non-small cell lung cancer.

Using data from over 500 CAR cell clinical trials, researchers hope to improve patient-trial matching and future immunotherapy designs.

The CVS-Tempus partnership aims to streamline the cancer care process for patients from the point of prescribing onwards and connect patients with local trials.

Transgene and NEC are working together to use artificial intelligence to tailor immunotherapy to individual patients.

CStone and Blueprint enrolled the first patient in a trial exploring the combination of the FGFR4 inhibitor fisogatinib and a PD-L1 inhibitor.

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