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non-small cell lung cancer

Results from the CheckMate-227 trial provided evidence for the use of nivolumab and ipilimumab in combination, while the FLAURA study focused on osimertinib.

An interim analysis of the IMpower110 study showed that the drug performed better as a first-line treatment than chemotherapy in these patients.

The drugmaker will present data from the Impower110 trial at an upcoming meeting and submit the data to regulatory authorities.

As labs implement TMB workflows in-house, studies are showing that its is possible to validate assays with cutoff points remaining stable across complex clinical cohorts and in different drug contexts.

Although the FDA has already approved the regimen in this indication after seeing its impact on progression-free survival, the latest data speaks to its impact on survival. 

The firms plan to use Thermo Fisher's Oncomine Dx Target test to identify cancer patients with RET alterations who might benefit from Lilly's LOXO-292.

The researchers aimed to develop a test that could help clinicians determine whether a patient would respond to therapy, before the onset of treatment.

This is the third drug the agency has approved with a pan-cancer indication.

Progression-free survival times were comparable for EGFR-mutated non-small cell lung cancer cases treated with a combination of erlotinib and bevacizumab treatment or erlotinib.

An updated analysis from the GioTag study supports the rationale for giving Gilotrif followed by Tagrisso in patients with EGFR Del19-positive lung cancer.

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