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Drug Discovery & Development

News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.

PMV Pharma Begins Trial of Investigational Drug in p53-Mutated Cancers

The Phase I/II trial of PC14586 will involve patients with advanced solid tumors characterized by the p53 Y220C mutation.

AUM Biosciences, Newsoara Biopharma Partner on Targeted Cancer Drug Development in Greater China

Through the partnership, Newsoara will develop and commercialize up to six targeted agents in greater China, while AUM will retain rights to the agents.

Bio-Path Holdings Doses First Patient in Phase I Lymphoma, Leukemia Trial

The trial is evaluating BP1002 to treat lymphoma and chronic lymphocytic leukemia patients whose tumors overexpress the protein BCL-2.

PMC Report Outlines Strong Growth, Future Challenges for Personalized Medicine Industry

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As adoption of personalized medicines has accelerated over the last four years, so has the number of marketed genetic and exome tests.

Achilles Therapeutics Raises $69.6M to Advance Personalized T-Cell Therapies

The UK-based firm will use the funds to advance its bespoke neoantigen-targeting T-cell therapies for solid cancers including melanoma and NSCLC.

Nov 18, 2020

Oblique Therapeutics Raises $11M to Advance Drug for KRAS-Mutated Cancer, Expand Globally

Nov 18, 2020

Elevation Oncology Raises $65M in Series B Funding Round

Nov 18, 2020

Indivumed, Ultivue Sign Deal to Integrate Cancer Tissue Analysis Technologies

Nov 17, 2020

Research Groups Fund Phase III Trials of Pfizer's Lorbrena in Pediatric Neuroblastoma

Nov 13, 2020

Greenwich, Baylor to Launch Phase III Immunotherapy Trial for Breast Cancer Recurrence Prevention

Nov 12, 2020

Jubilant Therapeutics, OneThree Biotech ID Biomarkers for LSD1, HDAC6 Inhibitor

Nov 11, 2020

Five Prime Therapeutics' FGFR Inhibitor Improves Survival in Gastric Cancer Trial

Nov 10, 2020

HitGen Outlicenses TRK/ROS1 Inhibitor to Baiyunshan for Development in Mainland China

Nov 10, 2020

Merck Halts Phase III Keytruda, Yervoy NSCLC Study

Nov 04, 2020

LianBio to Begin Infigratinib Phase III Trial in Bile Duct Cancer

Nov 03, 2020

Daiichi Sankyo, AstraZeneca Begin Head-to-Head Breast Cancer Trial of Enhertu, Kadcyla

Nov 02, 2020

Genprex to Combine Reqorsa With Checkpoint, EGFR Inhibitors in Lung Cancer Studies

Oct 30, 2020

Early Data in Hand, Verastem Marches Ahead With RAF-MEK Inhibitor Program in KRAS-mutated Cancers

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Oct 29, 2020

Atyr Pharma, Medical University of South Carolina Partner to Develop NRP2-Targeted Antibodies

Oct 27, 2020

Transgene's Vaccine for HPV16-Related Cancers Shows Anti-Tumor Activity With Bavencio

Oct 27, 2020

Pfizer Turns to Health Social Network to Find Patients With Rare Lung Cancer Genetic Variants

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Oct 26, 2020

Revolution Medicines Expands Development of SHP2 Inhibitor in KRAS-Mutated Cancers

Oct 23, 2020

Sumitomo Dainippon Pharma Doses First Patient in Dubermatinib Arm of AML Umbrella Trial

Oct 22, 2020

Ideaya Biosciences, Broad Institute Partner on Synthetic Lethality-Based Cancer Drug Discovery

Oct 19, 2020

Kazia Therapeutics' Paxalisib to be Evaluated in Glioblastoma Study

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In Drug Discovery & Development

  1. PMV Pharma Begins Trial of Investigational Drug in p53-Mutated Cancers

  2. AUM Biosciences, Newsoara Biopharma Partner on Targeted Cancer Drug Development in Greater China

  3. Bio-Path Holdings Doses First Patient in Phase I Lymphoma, Leukemia Trial

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