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Gene Expression Research

The latest news about RNA-seq, gene expression profiling, and transcriptome sequencing.

NCI researchers performed a multi-platform study to elucidate the factors that can contribute to a patient's better-than-expected response to a drug.

The researchers said their findings could explain improved outcomes of sarcomatoid tumors to checkpoint blockade versus antiangiogenic therapies alone.

Researchers showed benefit from chemotherapy in patients classified as high risk by the test, independent of their EGFR mutation status.

The aggressive subtype, uncovered by a team of researchers in Germany, may also be susceptible to targeted therapy that blocks interferon signaling.

The study found immunomodulatory and angiogenesis gene expression signatures, mutational profiles, and HLA types could help predict how patients respond to therapy.