Genomics: Clinical Implementation

This channel includes news headlines and educational resources regarding the clinical implementation of genomics assays, including development, validation, quality control, standardization, and the practical and commercial considerations for labs adopting these tests.

Oncocyte AACR Data Expands Potential Applications for Immunotherapy Response Predictor

The firm presented evidence that its DetermaIO gene expression test can help predict which bladder cancer patients are likely to respond to immune checkpoint inhibitors.

Liquid Biopsy MRD Detection Eyed as Decision Tool for Oligometastatic Colorectal Cancer Patients

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If the team is successful in expanding on the results that they reported last month, it could open a new application for the still nascent circulating tumor DNA technology.

Genetron Health Updates Data from Prospective Liquid Biopsy Liver Cancer Screening Study

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The results represent a significant improvement over currently used screening tools and are spurring renewed LDT commercialization and regulatory submission efforts.

GeneFirst Aims to Prove Clinical Feasibility for ATOM-Seq Colorectal Cancer Detection Test

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The company is collaborating with the University of Leeds under a new grant, aiming to collect prospective validation and economic data that could support clinical adoption.

AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic

Laboratory staffing and supply shortages limited patient access to cancer screening tests, and the pandemic decreased the development and validation of new tests.

Feb 19, 2021

BRCA2 Variants of Unknown Significance Reclassified Through Functional Data Additions

Feb 18, 2021

MSK Study Underscores Need to Validate Cancer-Specific Tumor Mutational Burden Cutoffs

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Feb 16, 2021

Circulating Tumor DNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases

Feb 16, 2021

MSK Team Explores Clinical Utility of Germline Testing for Pediatric Cancer Patients

Feb 08, 2021

Sophia Genetics, Spanish Lung Cancer Group Team up to Predict Lung Cancer Treatment Response

Feb 05, 2021

Guardant Health Turns to Tumor Tissue Sequencing to Broaden Offering

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Feb 04, 2021

Belgian Society of Medical Oncology to Study Value of Genomic Profiling for Cancer Patients

Feb 02, 2021

Genomic Testing Cooperative to Provide Free Molecular Profiling for Underserved Cancer Patients

Jan 20, 2021

CMS Finalizes Blood-Based Colon Cancer Screening NCD with Non-Coverage for Epi ProColon

Jan 11, 2021

Multi-Cancer Molecular Screening Assays Primed for Clinical Implementation in 2021

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Jan 11, 2021

Grail Inks Deals With Amgen, AstraZeneca, Bristol Myers Squibb for MRD Test Development

Dec 29, 2020

My Gene Counsel, Genomet Develop Decision Support Solution for Precision Cancer Care

Dec 18, 2020

UK Launches Public-Private iDx-Lung Consortium to Improve Early Detection of Lung Cancers

Dec 09, 2020

Nonprofit Friends of Cancer Research Launches Public-Private HRD Harmonization Project

Nov 24, 2020

Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves

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Nov 23, 2020

Tumor, Germline Testing of Cancer Patients Can Give Discordant Results

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Nov 17, 2020

Diagnostics Firms, Lab Providers Form Genomic Profiling Coalition

Nov 11, 2020

Adaptive Biotechnologies, GlaxoSmithKline Collaborate on MRD Testing

Nov 02, 2020

Regulatory Documents for Newly Approved Liquid Biopsy NGS Panels Detail Diverse Test Claims, Methods

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Oct 27, 2020

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Genomics: Clinical Implementation

Oncocyte AACR Data Expands Potential Applications for Immunotherapy Response Predictor

Liquid Biopsy MRD Detection Eyed as Decision Tool for Oligometastatic Colorectal Cancer Patients

Genetron Health Updates Data from Prospective Liquid Biopsy Liver Cancer Screening Study

GeneFirst Aims to Prove Clinical Feasibility for ATOM-Seq Colorectal Cancer Detection Test

AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic

BRCA2 Variants of Unknown Significance Reclassified Through Functional Data Additions

MSK Study Underscores Need to Validate Cancer-Specific Tumor Mutational Burden Cutoffs

Circulating Tumor DNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases

MSK Team Explores Clinical Utility of Germline Testing for Pediatric Cancer Patients

Sophia Genetics, Spanish Lung Cancer Group Team up to Predict Lung Cancer Treatment Response

Guardant Health Turns to Tumor Tissue Sequencing to Broaden Offering

Belgian Society of Medical Oncology to Study Value of Genomic Profiling for Cancer Patients

Genomic Testing Cooperative to Provide Free Molecular Profiling for Underserved Cancer Patients

CMS Finalizes Blood-Based Colon Cancer Screening NCD with Non-Coverage for Epi ProColon

Multi-Cancer Molecular Screening Assays Primed for Clinical Implementation in 2021

Grail Inks Deals With Amgen, AstraZeneca, Bristol Myers Squibb for MRD Test Development

My Gene Counsel, Genomet Develop Decision Support Solution for Precision Cancer Care

UK Launches Public-Private iDx-Lung Consortium to Improve Early Detection of Lung Cancers

Nonprofit Friends of Cancer Research Launches Public-Private HRD Harmonization Project

Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves

Tumor, Germline Testing of Cancer Patients Can Give Discordant Results

Diagnostics Firms, Lab Providers Form Genomic Profiling Coalition

Adaptive Biotechnologies, GlaxoSmithKline Collaborate on MRD Testing

Regulatory Documents for Newly Approved Liquid Biopsy NGS Panels Detail Diverse Test Claims, Methods

FDA Approves Foundation Medicine Liquid Biopsy Test as CDx for Three Targeted Therapies