Genomics: Clinical Implementation
This channel includes news headlines and educational resources regarding the clinical implementation of genomics assays, including development, validation, quality control, standardization, and the practical and commercial considerations for labs adopting these tests.
Natera Minimal Residual Disease Test Predicts Oligometastatic CRC Patient Outcomes in New Study
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Investigators analyzed blood samples from patients at two time points after curative-intent surgery, finding that ctDNA MRD status was highly predictive of outcome.
Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System
Under the deal, DUHS will establish PGDx's next-generation sequencing-based Elio Tissue Complete platform for the genomic profiling of cancer in its lab.
Researchers used real-world data to identify low NGS testing rates, particularly among Black patients, suggesting many aren't getting precision medical treatment.
Lynparza Benefit in Early BRCA-Mutated Breast Cancer Reignites Universal Genetic Testing Discussion
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The OlympiA trial showed a disease-free survival benefit with adjuvant PARP inhibitor therapy for early-stage, BRCA1/2-mutated, HER2-negative breast cancer patients.
Tool Detects Pediatric Bone Tumors From Liquid Biopsies Based on Epigenetic Profiles
Epigenetic signatures of Ewing sarcoma affect cell-free DNA fragmentation patterns and can be used to detect cancer.