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Microarrays & Multiplexing

News on microarrays, multiplexing, genotyping, cytogenetics, gene expression profiling in genetics, genomics, and molecular diagnostics.

Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance

The study suggested that ALL glucocorticoid resistance stemming from alterations that drive down CELSR2 levels might be combated with the BCL2-targeting drug venetoclax.

ACT Genomics, UCSD Partner for Tumor Microenvironment Immunotherapy Study

The company is hoping its technology can help predict which melanoma patients will respond to checkpoint inhibition using immune-related gene expression signals.

Custom NanoString Assay Detects Bowel Cancer Subtypes, May Help Guide Therapies

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The researchers have used nCounter, an FDA-cleared platform from NanoString Technologies, to develop their gene expression assay for subtype classification.

Agendia, Imegen Ink Distribution Deal for Breast Cancer Tests in Spain, Portugal

MammaPrint classifies patients as either high risk or low risk of recurrence over a 10-year period while BluePrint classifies patients by breast cancer subtype.

Almac Assay's Ability to Stratify Esophageal Cancer Patients Demonstrated by UK Researchers

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The test relies on a signature that Almac developed for stratifying breast cancer patients, but which, as the researchers showed, can be used in other cancers as well.

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