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Microarrays & Multiplexing

News on microarrays, multiplexing, genotyping, cytogenetics, gene expression profiling in genetics, genomics, and molecular diagnostics.

New Data Support Role of Agendia BluePrint Test in Refining Breast Cancer Subtypes

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At the American Society of Clinical Oncology's virtual meeting, investigators presented two new studies of BluePrint classification patterns.

Breast Cancer Subtypes Vary With Indigenous Ancestry in Latin American Women

Women with breast cancer from Peru, Mexico, or Colombia who had greater Indigenous American ancestry were more likely to have HER2-positive tumors.

Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance

The study suggested that ALL glucocorticoid resistance stemming from alterations that drive down CELSR2 levels might be combated with the BCL2-targeting drug venetoclax.

ACT Genomics, UCSD Partner for Tumor Microenvironment Immunotherapy Study

The company is hoping its technology can help predict which melanoma patients will respond to checkpoint inhibition using immune-related gene expression signals.

Custom NanoString Assay Detects Bowel Cancer Subtypes, May Help Guide Therapies

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The researchers have used nCounter, an FDA-cleared platform from NanoString Technologies, to develop their gene expression assay for subtype classification.

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