St. Jude
Experts are working through challenges to make low-cost sequencing available at resource-limited hospitals around the world, starting with an institution in Pakistan.
Proof-of-Principle Study Points to Possibility of Monitoring Pediatric ALL With Plasma Samples
Capture-based blood plasma sequencing helped track disease persistence or relapse and identify microbes that may cause infection in the immunosuppressed patients.
Polygenic Scoring Shows Promise in Guiding Induction Chemo in Pediatric AML in Early Research
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A JCO study details early efforts to develop a polygenic score to predict whether patients are likely to respond to cytarabine, though race-based differences need to be addressed.
Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy
The study found certain patients did not benefit from lower doses of radiation therapy, suggesting the need for molecular selection.
Genetic Loci Influence Risk of Cardiomyopathy in Pediatric Cancer Survivors of African Ancestry
Researchers uncovered genetic loci that may influence why childhood cancer survivors of African ancestry are more likely to develop therapy-linked cardiomyopathy.