University of Michigan
Polygenic Risk Scores for Breast, Prostate Cancer Adaptable for Cross-Ancestry Use, Study Shows
The researchers said the approach could be a short-term measure while genetic studies of more diverse ancestral populations are performed.
Drug Combination, Biomarker Search Continues in Urothelial Cancer After Mixed ESMO Trial Data
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Following variable Phase III outcomes, investigators are searching for more informative biomarkers than PD-L1 expression in advanced urothelial carcinoma cases.
Germline Results From Tumor-Normal Sequencing Guides Precision Therapy in Advanced Cancer Patients
Two studies presented at ASCO's virtual annual meeting demonstrated the clinical utility of germline findings in guiding treatment decisions in cancer.
A pilot project showed that clinics using the InheRET tool were able to gather more complete family history information from patients, which is important for further cancer risk evaluation.
BRCA Risk Variants May Coincide With Breast Cancer Treatment Differences
Using data from cancer registries, investigators saw apparent disparities in the surgical interventions and treatments used for breast cancer patients with inherited cancer risk.