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By Cullinan Oncology

A Platform-Agnostic Approach to Building a Diversified Immuno-Oncology Portfolio

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Platform- or modality-agnostic approaches to therapeutic agent design may offer more promise than platform-centric approaches. Rather than deploying a single strategy, researchers can allow the biology to dictate therapeutic design.

By Oxford BioDynamics

Q&A: How a Noninvasive Blood Test is Changing Immunotherapy Treatment

The noninvasive test evaluates eight 3D genomic markers and is the only test that returns a binary result to the ordering physician with high accuracy: “low probability” or “high probability” of response to an ICI.

By F. Hoffmann-La Roche Ltd.

Perspective: Accessing Innovation at the Point of Care with Comprehensive Genomic Profiling

Precision oncology will only be a reality for all patients if there is collaboration between the different stakeholders within the healthcare system — such as industry partners, academia, and regulatory bodies — to increase patient access.

By Biognosys

Next-Generation Proteomics Delivers Insights Across the Oncology Pipeline: Highlights from the AACR 2022 Annual Meeting

Advances in proteomics are improving cancer biomarker discovery, drug discovery, and drug target validation.

By Biognosys

Mass Spectrometry is Fueling Advancements in Plasma Proteomics for Biomarker Discovery

Plasma and serum are brimming with potential protein biomarkers that can provide detailed information about health and disease mechanisms without the need for invasive medical procedures.

By F. Hoffmann-La Roche Ltd.

New TMB Recommendations Help to Guide Treatment Decisions in Oncology

Recent recommendations from the ESMO Precision Medicine Working Group and National Comprehensive Cancer Network, coupled with US Food and Drug Administration review and approval, have highlighted the use of tumor mutational burden testing in clinical practice for a number of different tumor types. 

By Biognosys

Going Beyond Genomics with Next-Generation Proteomics to Accelerate Precision Oncology

In recent years, the field of proteomics has undergone a transformation, enabling quantitative analysis of more than 10,000 proteins across thousands of samples, while advances in structural chemoproteomics allow researchers to map drug binding sites with unprecedented resolution. These next-generation proteomics approaches are driving significant progress in precision oncology. 

By F. Hoffmann-La Roche Ltd.

Putting Personalized Healthcare at the Heart of Clinical Practice

The COVID-19 pandemic has caused massive disruption to cancer care. Delays in diagnosis and treatment highlight the importance of establishing a personalized healthcare approach that provides tailored care, integrates innovation, and supports equal access to cancer care.