cancer subtypes
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands.
Large-Scale Cancer Genome Analysis Reveals Mutation Clusters That Can Inform Prognosis
With genome sequences for thousands of tumors, researchers identified somatic mutation clusters, mechanisms behind them, and potential ties to patient outcomes.
Breast Tumor Features Reflecting Germline Variants May Improve Risk Prediction Models
Researchers spelled out relationships between germline variants in nine breast cancer susceptibility genes and tumor features ranging from molecular subtype to size.
Certain Childhood ALL Subtypes Linked to Genetic Ancestry
With sequence data for thousands of cases in children and young adults, researchers identified tumor molecular subtypes that coincided with patients' genetic ancestry.
Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups
Researchers identified 12 multiple myeloma subgroups based on mutation, copy number, chromosomal rearrangement, and expression features in more than 650 tumors.