methylation
At the AACR annual meeting, both companies shared new data on their technologies' performance in detecting early and late-stage cancers.
New Epigenomic Biomarker Could Predict CAR T-Cell Therapy Resistance in Advanced Childhood Leukemia
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At AACR, researchers described how pediatric ALL patients who don't respond to anti-CD19 CAR T-cell therapy have cancers with a unique, stem cell-like epigenome.
Singlera Genomics, Astellas Pharma Partner to Study Drug Reactions
The collaborators will design assays using Singlera's methylation-based mTitan platform for monitoring biological responses to drug treatment.
The company aims to release an initial tissue-based prognostic this year, with a less-invasive sponge-sampling version for screening high-risk individuals to follow in 2023.
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands.