Microsatellite Instability Testing
The latest news on microsatellite instability testing.
UK's NICE Recommends Approval of Opdivo, Yervoy for MSI-High, MMR-Deficient Colorectal Cancer
The combination treatment has already been approved in the US and recommended for approval in this setting in Europe.
NICE Recommends Keytruda for Metastatic MSI-High, Mismatch Repair-Deficient Colorectal Cancer
The draft guidance recommends Merck's immunotherapy be available to patients in the UK with untreated MSI-high or dMMR colorectal cancer.
TMB-High Status Does Not Predict Opdivo-Yervoy Response in Pan-Tumor Analysis
In a retrospective analysis, tumor mutational burden was not associated with improved responses to combination immunotherapy, researchers found.
Chinese Regulators Accept Henlius' Serplulimab New Drug Application
The company is seeking approval for the anti-PD-1 monoclonal antibody in advanced, MSI-high solid tumors that are refractory to standard treatments.
European Commission Approves GSK's Dostarlimab in Endometrial Cancer
The approval marks the first anti-PD1 antibody available in Europe to treat recurrent or advanced endometrial cancer.
Apr 14, 2021
Mar 25, 2021