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CHICAGO (GenomeWeb) – A team led by the Institute of Cancer Research in the UK has used exome sequencing in an effort to tease out prostate cancer molecular features that are associated with a response to the checkpoint blockade immunotherapy drug pembrolizumab (Merck's Keytruda).

At the American Society of Clinical Oncology meeting here this week, Johann de Bono, director of the ICR's drug development unit, shared data from the Keynote-199 study, a Phase II trial comparing pembrolizumab response in 258 metastatic prostate cancer cases with or without tumor expression of PD-L1.

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Jul
23

This webinar will discuss how the Molecular Pathology Laboratory at the University of Oklahoma (OUMP) is using a new quality improvement model to support molecular testing of oncology patients. 

Jul
30
Sponsored by
Mission Bio

This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse.