biomarker detection
New Epigenomic Biomarker Could Predict CAR T-Cell Therapy Resistance in Advanced Childhood Leukemia
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At AACR, researchers described how pediatric ALL patients who don't respond to anti-CD19 CAR T-cell therapy have cancers with a unique, stem cell-like epigenome.
Adding Genetic Information to PSA Improves Biomarker's Performance in Prostate Cancer Diagnosis
AACR research showed that incorporating a genetic risk score of prostate-specific antigen variation made the controversial biomarker more sensitive and specific.
Novartis, Lantheus Partner on PSMA Imaging-Based Patient Selection in Pluvicto Trials
The partners will use Lantheus' Pylarify imaging agent to select PSMA-positive mCRPC patients for trials of Novartis' targeted radiopharmaceutical Pluvicto.
Zentalis Pharmaceuticals, Caris Life Sciences Ink Precision Oncology Partnership
Caris will use its platform to sequence solid tumor patients' full exomes and transcriptomes to determine eligibility for Zentalis' Wee1 inhibitor ZN-c3.
Poor Oncologist-Patient Communication Adding to NSCLC Biomarker Testing Disparities, Survey Finds
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Survey results from the advocacy organization LUNGevity revealed stark disparities in biomarker testing rates and communication patterns among NSCLC patients.