RNA-seq
Overexpressed Cancer Testis Antigen Could Reflect Therapeutic Target in Liver Cancer
A new study has found that MAGEA3 is overexpressed in aggressive liver cancer and has a role in upregulating survivin to inhibit apoptosis.
Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease
Researchers saw convergent subclones crop up in early-stage, estrogen receptor-positive breast cancers that dodged endocrine- and CDK4/6 inhibitor-based therapies.
Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target
The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery.
The company expects to launch testing for advanced cancer patients this year, with studies now running to expand to cancer screening and monitoring applications.
Early-Stage Lung Cancer Development Traced in Single-Cell RNA Sequencing Study
Researchers mapped the changes normal cells in the lung undergo as they evolve into cancerous cells and identified new targets for treatment.